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Combining BPC-157 and Testosterone Replacement Therapy (TRT) Despite the lack of direct testosterone-boosting effects, there are rational clinical reasons to combine BPC-157 with TRT

doi: 10.1159/000441768

Gwyer, Wragg & Wilson (2019), "Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing," Cell and Tissue Research 377(2):153-159 [PubMed]
Effective patient guidance helps reinforce practitioner recommendations before outside messages introduce

The two key components are the peptide itself and the solvent used to bring it into solution

EGF is bioactive but barrier-limited: the molecule does what it does only if it reaches the keratinocyte layer, and standard topical formulations deposit most of it on the stratum corneum where it has no relevant receptor
