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The underlying mechanisms include chronic inflammation, oxidative stress, mitochondrial dysfunction, and ER stress

It has been shown that an exogenous addition of GSH could effectively reduce radiation-induced micronuclei [33] and chromosome aberrations in different systems [34], including the muntjac lymphocyte cultures [35]

Studies exploring the influence of curcumin on DNA methylation are summarized in Table 1

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Combination index (CI) was calculated using the CompuSyn software, CI 1.0 was defined as antagonism

J Child Neurol 23(10):11791185 Kim HM, Rim HK, Shin T, Kim JJ, Park ST, Oh JM et al (2000) Human chorionic gonadotropin induces nitric oxide synthesis by murine microglia