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Defective mitochondria produce excessive free radicals, leading to oxidative stress and impairing cellular mechanisms

Big implications for access, pricing, and the peptide ecosystem

79 KoryckaJLachAHegerEBoguslawskaDMWolnyMToporkiewiczMet al

These findings support a constraint on the movement of energy substrates between axons and glia in the ONH and the early breakdown of neuro-glial metabolic coupling

Alwohoush, J

For example, the glioma-toxic impact of temozolomide (TMZ) can be potentiated by xCT inhibitors, such as erastin, thus enhancing the efficacy of TMZ (87)
