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For CKD patients, the leading cause of mortality is cardiovascular (CV) disease [3]

103 Among these, oral administration offers several advantages, such as noninvasiveness, ease of self-administration, flexible dosing, and elimination of sterile preparation requirements, making it particularly attractive for improving patient adherence and satisfaction

Statistical comparisons between means were performed using an unpaired Students t-test to assess differences between two groups

those which induce the enzyme system capable of carcinogen detoxification, and those which can react with cancer-causing species and prevent their reaction with the cellular targets (Steward and Brown, 2013