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M1 macrophages exhibit bactericidal, pro-inflammatory, and anti-tumor functions, whereas M2 macrophages are primarily involved in tissue repair and anti-inflammatory processes and pro-tumor activities 88

After loading with PNPs, Dessy and colleagues developed nanoparticles loaded with anti-inflammatory Dead Sea Water (DSW) minerals, including calcium, magnesium, sodium, potassium, zinc, and strontium