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The induction of the model led to an increase of ROS and cell death, related to the activation of apoptosis signal-regulating kinase 1 (ASK1 also known as MAP3K5), as well as in the activation of JNK and p38
The pharmaceutical industry has spent decades trying to develop effective treatments for fatty liver disease
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doi: 10.1016/S0002-9440(10)62320-6 [DOI] [PMC free article] [PubMed] [Google Scholar] 115.Borbr I, Lisztes E, Tth BI, et al
Our transcriptomic profiling revealed a previously uncharacterized transcriptional trajectory in skin-infiltrating eosinophils
Therefore, UA could protect mice against the effect of CPZ-mediated demyelination on memory performance
