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As mentioned previously, polymorphic variants of -GCS have been linked to specific diseases
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Lersen K, Walter RD, Mller S (2000) Plasmodium falciparum-infected red blood cells depend on a functional de novo synthesis of glutathione attributable to an enhanced loss of glutathione
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Chiral auxiliary In 1984, Johnson and Elliott reported the use of R , R -2,4-pentanediol (PTSA) as a chiral auxiliary in a TiCl 4 -catalyzed aldol-type reaction to synthesize aldol esters in excellent yields and high diastereoselectivities
