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Although it was never proposed that this condition was a general feature of critical illness, the idea of glutamine supplementation was embraced for general use, not confined to patients with hypoglutaminemia only

SRC-3 over-expression is also positively correlated with increased levels of HER-2/neu, poor disease-free survival and tamoxifen resistance in tamoxifen-treated breast cancer cells [73]

clinical effect sizes vary by indication, dosing, individual factors, and adherence

Moreover, NOX-4 is upregulated in lungs of mice treated with bleomycin and humans with IPF [24]
