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Excess iron is known to replace zinc in the N-terminal DNA-binding 'zinc finger' of the estrogen receptor, resulting in increased ROS formation

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10.1073/pnas.1018987108 [DOI] [PMC free article] [PubMed] [Google Scholar] 185.Goldberg JL

To reconstitute, wipe both stoppers, let the BAC water run down the inside vial wall, and swirl gently without shaking

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