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If you have blood vessel disease or conditions that restrict blood flow into the penis, penile injections may not work for you

When B12 levels become too low, people may experience symptoms such as: Fatigue or low energy Memory or concentration problems Numbness or tingling in the hands and feet If B12 deficiency becomes severe and lasts a long time, it can lead to nerve damage

But with the right approach, thigh injections can be nearly painless

Several tendon-focused studies demonstrated accelerated healing in transected Achilles tendon models alongside improved fibroblast survival and migration

Measuring serum biomarkers such as B 12 or MMA is neither helpful nor indicated in assessing or monitoring clinical improvement.38 Base the injection frequency on symptoms, and not on biomarker assessment