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These nanocarriers could also improve transport across the olfactory and trigeminal pathways by prolonging nasal residence time, enhancing epithelial penetration and enabling targeted delivery to the upper nasal regions (Dhuria et al., 2010

[DOI] [PubMed] [Google Scholar] 41.Veljaca M., Chan K., Guglietta A

9496,292,323325 These protective mechanisms include the up-regulation of pro-angiogenic factors such as isoform 164 of VEGF-A that protect against capillary rarefaction, and increased expression of matrix metalloproteinases that effect repair and protect against fibrosis by degrading extracellular matrix

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doi: 10.2337/diabetes.54.6.1615

Supporting responsible use minimizing risks