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These effects collectively contribute to abnormal neurodevelopmental trajectories and cognitive or behavioral dysfunction observed in affected individuals

According to the CDC, acetaminophen overdose leads to approximately 56,000 emergency room visits and 2,600 hospitalizations annually in the U.S., making it a leading cause of acute liver failure

However, after higher overdoses of APAP, no difference in injury was observed between male and female mice [107]

Biochim Et Biophys Acta (BBA)-Bioenergetics

This, however, is still well within the measured range of glutathione concentrations in rml1

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