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In PKM2 fl/fl SM-MHC-CreERT2 mice, SM22 and SM-MHC expression were increased, while vimentin and osteopontin expression were decreased, reflecting the association between glycolysis inhibition and the maintenance of VSMC contractile phenotype

20 In current redox biology concepts, low levels of ROS trigger the activation of signaling pathways, initiating various biological events

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[DOI] [PubMed] [Google Scholar] 217.Liu Y, Sun Y, Guo Y, Shi X, Chen X, Feng W, et al

McCoull W, Barton P, Broo A, Brown AJH, Clarke DS, Coope G, Davies RDM, Dossetter AG, Kelly EE, Knerr L, MacFaul P, Holmes JL, Martin N, Moore JE, Morgan D, Newton C, sterlund K, Robb GR, Rosevere E, Selmi N, Stokes S, Svensson TS, Ullah VBK, Williams EJ (2013) Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity

Mayo Clinic, Feb