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The aqueous extract of Scrophularia radix (RSAE) enhances antioxidant enzyme activities such as SOD and GSH-Px, reduces oxidative stress, regulates the Bcl-2/Bax balance, and inhibits MAPK phosphorylation

[DOI] [PubMed] [Google Scholar] 153.Reyes D.R., Gomes M.J., Rosa C.M., Pagan L.U., Damatto F.C., Damatto R.L., DePra I., Campos D.H., Fernandez A.A., Martinez P.F., et al

doi: 10.1016/j.biopha.2023.114586 87 LohseM

Palacios et al

However, a more recent report demonstrated a reduction in nicotine self-administration by LY379268, but no effect on cocaine self-administration (Justinova et al., 2016)
