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Tail snips from founder mice were submitted for Sanger sequencing to confirm homozygous deletion

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A randomized, double-blind, placebo-controlled crossover clinical trial found that treatment with oral ALA (1200 mg/8 weeks) resulted in a significant reduction in both waist circumference and body weight [44]

The rats were then randomly divided into five groups as follows: Group 1, the normal control group (CON
