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Macrophages can produce relatively large amounts of nitric oxide, especially the M1 inflammatory macrophage, via increased concentrations of the enzyme inducible nitric oxide synthase, which may be stimulated by LPS or other immune activator exposure

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J Neurochem 16:191203 Eid T, Ghosh A, Wang Y, Beckstrm H, Zaveri HP, Lee TS, Lai JC, Malthankar-Phatak GH, de Lanerolle NC (2008) Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats

A defining molecular hallmark is global DNA hypomethylation in lymphocytes, especially CD4+ T cells, which associates with disease activity and stabilizes a type-I-interferon-driven program

TUDCA (short for tauroursodeoxycholic acidtry saying that five times fast!) is a bile acid naturally produced in small amounts by your liver

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation