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PGI 2 , one of the prostanoids of arachidonic acid metabolism, is a potent vasodilator that inhibits platelet aggregation, leukocyte adhesion, and VSMC cell proliferation [87]

Treatment with L-ca 100 and L-ca 200 significantly decreased the BUN, creatinine and uric acid in comparison to the MSG group

The lower RER value in the current study may be due to an increase in the L-carnitine content in skeletal muscle, and if indeed the content of L-carnitine increased, the proposed mechanism for L-carnitine uptake is thought to occur via a strong insulin response stimulating the activity of the Na + /K + pump, increasing extracellular Na + concentration