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For instance, in oral pills, the retention is not extended, with little absorption

Except for the seminal study of Cox et al

Durazzo et al

(PubMed) Fry PC, Fox HM, Tao HG

Plant Signal Behav 5(2):171175

Additionally, an open-label, single arm pilot trial (OPTIMA) was designed to assess the efficacy and safety of inhaled GM-CSF (Molgramostim nebulized solution) in treating NTM-PD in adults with non-CF bronchiectasis ( Although these data have not fully demonstrated the exact efficacy of NE inhibitors in the treatment of bronchiectasis, researchers continue to explore and optimize the therapeutic strategies for NE inhibitors, including the development of inhaled NE inhibitors to increase the concentration of the drug in the lungs and thus improve the clinical efficacy