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The course of treatment largely depends upon underlying health issues that caused a change in your hemoglobin count. Phlebotomy: In this treatment option, the doctor will use needles or syringes to remove blood from your body

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Although targeted therapies have improved outcomes, resistance remains a challenge, particularly in high-risk patients with TP53 mutations or unmutated immunoglobulin heavy-chain variable region (IGHV) genes (U-CLL)