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The practical evidence remains limited
Histopathological examination of major organs including liver, kidney, heart, brain, and reproductive tissues shows no treatment-related lesions
Last, development of new anti-TNF- forms and sophisticated TNFR targeting might optimize drug bioavailability, enhance their local efficacy and minimize adverse effects, while combination with other agents might refine disease outcomes using lower drug doses
K.KarimahR.et al
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Cholinergic Toxicity
