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NRS 4/10), and 57% had a painDETECT score 12

10.1017/S1041610211001141 Int

Am.J Med Genet

While overall decline rates were similar between groups, post-hoc subgroup analysis indicated slower cognitive decline in early-onset patients (aged 65 or younger) compared to placebo, as measured by the Alzheimer's Disease Assessment Scale cognitive subscale and Clinical Dementia Rating Scale [5][18]
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