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Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage
It has the ability to reduce neuro-inflammation which helps relieve the cognitive symptoms of conditions such as Lyme, Alzheimers disease, Parkinsons disease, and even post-concussion syndrome

Higher levels of O-GlcNAcylation have been demonstrated to protect against the toxic effects of Tau and amyloid- peptide [41, 42]

But yeah, I dont, there is not very much evidence at all for grams of vitamin C doing anything to prevent diseases that are relevant to human longevity

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The distribution of MTHFR SNPs is illustrated in Figure 3: 677TT: 58.4%, 677CT: 9.1%, Combined Heterozygoty (combo) 677CT/1298AC: 19.5%
