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Description
The accumulation of advanced glycation end products (AGEs) can also induce apoptosis (cell death) in fibroblasts, resulting in a significant loss of hyaluronic acid, collagen, and elastin

& Brestoff, J

Osteopat 2005, 13, 11

Hepatic fibroblast growth factor 21 is regulated by ppar and is a key mediator of hepatic lipid metabolism in ketotic states

This depletion may lead to compromised immunity, increased oxidative stress, and vulnerability to a range of health issues

Instead, it works downstream to protect cells from the damage that often results from metabolic activity
