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10.1158/1078-0432.ccr-13-0150 [DOI] [PMC free article] [PubMed] [Google Scholar] 69.Grozio A, Sociali G, Sturla L, Caffa I, Soncini D, Salis A, et al

5-Amino-1MQ and Metabolic Research Researchers studying 5-Amino-1MQ commonly focus on: Obesity research Weight management pathways Energy metabolism Endocrine signaling Adipose tissue studies Cellular metabolic regulation Published preclinical research involving NNMT inhibition has generated increasing interest in metabolic pathway modulation and energy balance studies

While the peptide appeared well tolerated in these trials, the absence of reproducible clinical benefit meant the molecule did not progress to approval or further late-stage studies