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Ethics declarations Ethics Approval and Consent to Participate All experimental procedures of this study were conducted under ethical committee supervision of Iran University of Medical sciences (Tehran, Iran) that was in accordance to NIH guidelines for the care and use of laboratory animals

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30 mtDNA contains 37 genes that code for 13 subunits of complexes I, III, IV and V, as well as the machinery required to translate and transcribe the mtDNA genes into ETC complex subunits

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