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Self-treatment can lead to addiction to NSAIDs and serious consequences related to changes in the digestive system, kidneys, liver, or respiratory system in people with asthma

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This is probably because the understanding of and related studies on nasal-brain drug delivery are limited

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Here, Coyle and Paul discuss drugs with promising new mechanisms under development for schizophrenia, including those targeting glutamatergic and cholinergic signalling.