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Cleavage of the C-terminal NCI domain of type XV collagen results in the production of restin, a molecule shown to possess antiangiogenic properties in vitro by inhibiting bFGF-induced EC migration and in a xenograft carcinoma model in vivo 107,108

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doi: 10.1016/s0002-9440(10)61243-6

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Within each region, vary the exact spot by at least 1 inch between injections