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Fold change in the expression represents the ratio between the averages of the gProcessed signals of the various groups and is expressed as log 2

Like LC, it is found in relatively high amounts in the brain [193]

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This reprogramming leads to the accumulation of metabolites such as lactate and ketone bodies, thereby lowering the pH of the tumor microenvironment, inhibiting the activity of effector T cells and NK cells, while promoting the infiltration of regulatory T cells and MDSCs, forming an immunosuppressive microenvironment