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A recent study found that 17% of people who have had a concussion have microbleedstiny hemorrhagesin their brains

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Tyurina YY, Polimova AM, Maciel E, Tyurin VA, Kapralova VI, Winnica DE, Vikulina AS, Domingues MRM, McCoy J, Sanders LH, Bayr H, Greenamyre JT, Kagan VE (2015) LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: implication for mitochondrial dysfunction in Parkinsons disease

For example, pre-treatment with a small molecule inhibitor of P300 significantly reduced the level of lactylation in a mouse model of ischemic stroke, helping to maintain neuronal activity and alleviate ischemic brain injury [46]

doi: 10.1038/s41598-023-45006-5