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doi: 10.1016/j.envint.2020.105783

Studies of postmenopausal women indicate that estrogen deprivation is associated with declining dermal collagen content, diminished elasticity and skin strength, loss of moisture in the skin, epidermal thinning, atrophy, fine wrinkling, and impaired wound healing

Our subsequent studies in human endothelial cells showed that the homocysteine metabolite, S-adenosylhomocysteine, a potent inhibitor of many methyltransferases, decreased tRNA Sec methylation to suppress GPx1 expression and activity [69]

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E

Intestinal brush border membranes, or microvilli, increase rapidly in the last 2 days of incubation, thereby expanding the intestinal surface area and increasing the digestive and absorptive capacities (41)

Therefore, blocking the undesirable actions of these enzymes is a therapeutic strategy for treating various pathological disorders