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Cisplatin: the first metal based anticancer drug

Im proximalen Tubulus wird es zu alpha-Ketoglutarat und Ammonium gespalten

In particular, MPEP (2-Methyl-6-(phenylethynyl)pyridine) and MTEP(2-Methyl-4-thiazolyl)ethynyl)pyridine) are non-competitive mGluR antagonists that protect against neuronal toxicity in vitro , using primary neurons from AD transgenic mice, by preventing A oligomer-induced dendritic spine loss (Um et al., 2013

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(2011) Mimics of the dimerization domain of hepatocyte growth factor exhibit anti-Met and anticancer activity

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