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A companion phase III trial reported a -10.9% reduction in visceral adipose tissue (a 21 cm decrease) in the tesamorelin group compared with -0.6% in the placebo group over the six-month efficacy phase, alongside significant improvements in trunk fat, waist circumference, and waist-hip ratio, with the authors concluding that tesamorelin reduces visceral fat by approximately 18% and improves body-image distress in HIV-infected patients with central fat accumulation, without significant side effects or disruption of glucose control

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Q: Is there an age limit or minimum

These results underscore a pivotal role for mPFC-derived CCK in shaping affective responses to social stress and suggest a promising molecular target for intervention in stress-related neuropsychiatric disorders

He W, Wang X, Zhan D, Li M, Wang Q, Liu J, et al
Hydrogen sulfide accelerates cell cycle progression in oral squamous cell carcinoma cell lines
