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However, because its half-life in circulation is only approximately 6 min, SOD cannot be directly administered as a therapeutic strategy [36]

Dimer (left) and monomer (right) ribbon diagrams of dmGSTD1 (PDB: 3MAK) overlayed with lipophilic surface representation

Suppression of NFS1 alone does not induce ferroptosis, but when cells produce large amounts of ROS, iron starvation induced by inhibition of NFS1 promotes ferroptosis

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Choice E: Unintended weight loss is a systemic symptom raising suspicion for a neoplastic process like an intramedullary spinal cord tumor

10.3233/jad-2008-15313 J
