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(116) reported that in MPTP-induced PD mice, intraperitoneal CUR at low (40 mg/kg), medium (80 mg/kg), and high (160 mg/kg) doses resulted in dose-dependent improvements in motor function and dopaminergic neuron protection

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Sensory symptoms usually develop first in the feet and handsreflective of the axon length, with longer neurites affected firstand manifest as numbness, tingling, paresthesias and dysesthesias induced by touch, warm or cool temperatures, impaired vibration and altered touch sensations

YS: Conceptualization, Writing original draft

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