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doi: 10.1186/s12940-017-0291-8 28 DehdashtiBNikaeenMAminMMMohammadiF

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Although only IL-1-induced cyclo-oxygenase 2 (COX2) production and IL-8 secretion could be attenuated by the ERK1/2-specific inhibitor PD98059, both TNF- and IL-1 activate ERK and induce the expression of IL-8 and IL-6 [128]