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We also performed the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) staining of tumors and hearts from the DOX and DOX/LAAM GSH-CQD groups

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The pathophysiology of MDD is multifactorial, involving dysregulation of monoamine neurotransmitters (serotonin, norepinephrine, and dopamine), dysfunction in GABAergic signaling, reduced neurogenesis and synaptic plasticity, and increased neurodegeneration