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In addition to variations in the total amount of melanin [8, 9], the size, distribution, and fate of melanosomes within keratinocytes are key determinants in the diversity in skin pigmentation [11, 17, 18]

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[Google Scholar] Trakulsrichai S, Sathirakul K, Auparakkitanon S, Krongvorakul J, Sueajai J, Noumjad N, Sukasem C, Wananukul W (2015) Pharmacokinetics of mitragynine in man

10.3389/fnmol.2014.00063 8 AyyadevaraS.BalasubramaniamM.GaoY.YuL