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Clinical trial NCT04050670 examined tirzepatide absorption at different sites and found something interesting

PMID: 37366315

IGF-1 DES (Des(1-3) IGF-1) is a 67-amino acid truncated form of IGF-1 with the first three amino acids (Gly-Pro-Glu) removed from the N-terminus

doi: 10.1016/S0946-672X(01)80009-2 42 KlevayL

1.2 Consensus recommendation 1.2.1 Any child presenting with acute hepatitis, chronic hepatitis, cirrhosis, or acute liver failure (negative for viral etiologies) should be screened for autoimmune hepatitis (LOE 3, Strong recommendation)

Blood Cancer J 4:e229 Tekautz TM et al (2005) Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy