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This period of time varies depending on whether the finding was minor or major

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Claudin proteins are small (2027 kDa) transmembrane proteins expressed in tissue- and cell-specific manner, 12, 13 with a total of 27 claudin family members having been identified to date

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Notably, controlled fluid flow introduces sustained perfusion and physiologically relevant shear forces, both of which modulate cellular behaviour and allow for a more accurate assessment of nanoparticle transport, distribution and cellular uptake than static in vitro models [175, 176]

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