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The mean IGF-1 standard deviation (SD) was not significantly different between the GHD and non-GHD groups (p = 0.23)

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Additionally, ELISA was performed to quantify secreted IL-6 and TGF- in co-culture media [2]

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Samples with a signal to noise ratio higher than the assay cut point in the screening assay were treated with excess AMG 966 in the confirmatory assay to assess specificity