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Annu Rev Pathol

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10.1016/b978-0-12-800102-8.00013-8 Kidney Development, Disease, Repair and Regeneration 118 ShenZ.KauttuT.SeppnenH.VainionpS.YeY.WangS.et al (2012)

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Oncogene 39 , 14291444 (2020)

For example, alginate possesses a large number of carboxyl groups in its polymer framework, which are converted into negatively charged carboxylate ions in alkaline conditions, leading to pH-responsive expansion that accelerates drug release [345]