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Within the research community, NNMT inhibition is studied in pre-clinical models for its relationship to the NAD+ salvage pathway, methyl-donor homeostasis, and adipocyte energy metabolism

AK received research grants from BMBF, Cendres + Metaux SA, Charit, Exthera, Mirobio, MorphoSys, Numares, Quintiles, and Reata Pharmaceuticals

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A sensitive whole blood assay detects antigen-stimulated cytokine release from CD4 + T cells and facilitates immunomonitoring in a phase 2 clinical trial of Nexvax2 in coeliac disease

Protocol: - KPV: 200-500 mcg/day oral or subcutaneous - GHK-Cu: 1-2 mg/day subcutaneous or topical - Duration: 6-8 weeks Best for: Inflammatory arthritis, autoimmune joint conditions, multi-joint inflammation in older adults

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