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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Panchaprateep R, Asawanonda P

428, Jan

Chen TH, Wang HC, Chang CJ, Lee SY

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By summarizing articles related to fatty acid metabolism and RF, we conclude that the dysregulation of the PPAR/PGC-1 core axis initiated by miRNAs such as miR-21, miR-150, miR-9-5p, and miR-495, along with the drive of CPT, a key enzyme in fatty acid oxidation, mediates lipotoxic cascades

Thus, through precise polarization control, macrophages act as pivotal regulators in tissue repair, temporal coordination of regeneration, and immune defense
