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These peptides are under consideration for addition to the FDAs list of bulk substances that may be used by compounding pharmacies

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Mechanistically, PL treatment increased reactive oxygen species (ROS) levels and induced ROS-mediated apoptosis in AML cells, which could be prevented by treatment with the antioxidant scavenger N -acetyl-cysteine and the pancaspase inhibitor Z-VAD(OMe)-FMK

Examination of the mechanisms involved in HDAC4 and 5-mediated apoptosis revealed that p53 acetylation of K120 tended to be higher ( p = 0.08

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Pasupulati, A