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Boyette-Davis J, Dougherty PM
24 According to Lipinskis rule of five, 35 panduratin A does not completely comply with the rule because of its high logP value, which may cause low water solubility and affect its oral bioavailability
An attractive feature of enterokinase and factor Xa is that after cleavage there is no additional amino acid residues on the protein structure, contributing to an intact end product (Choi et al., 2001, Hearn and Acosta, 2001, Jenny et al., 2003)
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