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2.2 Glutathione peroxidase 4 (GPX4): the master regulator of ferroptosis The central suppressor of ferroptosis is GPX4, a selenoprotein that reduces phospholipid hydroperoxides to their corresponding alcohols [70-72]

First episode psychosis and schizophrenia are systemic neuro-immune disorders triggered by a biotic stimulus in individuals with reduced immune regulation and neuroprotection

While such models provide significant mechanistic insights into APAP-induced hepatotoxicity, including pathways related to oxidative stress, mitochondrial dysfunction, and inflammasome activation, they may not fully recapitulate the complexity of human physiology

Silva LM, Alves JS, da Silva Siqueira EM, de Souza Neto MA, Abreu LS, Tavares JF, Porto DL, de Santis FL, Demarque DP, Lopes NP, Arago CF (2018) Isolation and identification of the five novel flavonoids from Genipa americana leaves

Mice from a different substrain and vendor, but fed similar lean and high-fat diets to this study, showed a predominance of the family Erysipelotrichaceae, of which Ileibacterium is a genus, in their cecal microbiomes 76