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We found that cells treated with either 6-AN or si-G6PDH exhibited higher ALP activity and formation of mineralized nodules, as well as increased expression levels of osteoblast differentiation-related genes and proteins ( Figures 5 , 6 ), indicating an enhancement in cellular osteogenic differentiation after inhibiting NADPH production
In the thick ascending limb of the loop of Henle, the defective receptors fail to inhibit the Na-K-2Cl cotransporter , leading to enhanced paracellular calcium reabsorption
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Science 220 , 101102 (1983)
