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Apoptosis 28(910):14691483 Fan J, Liu L, Lu Y, Chen Q, Fan S, Yang Y, Long Y et al (2024) Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis
Who Should Exercise Caution With Glutathione Injections

In contrast, we found the level of free GSH to degrade over time (F 1,14.39 = 42.9577
In addition to the KEAP1-dependent pathway, NRF2 degradation is regulated by an additional -TrCPdependent degradation pathway, via NRF2 phosphorylation by GSK3 in a PI3K-dependent manner (Hayes et al., 2015)

In summary, reduced glutathione adjuvant therapy plays an important role in improving the therapeutic effect of patients with chronic hepatitis B
