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Mechanical damage : Repeated actions like shaving, tweezing, threading, or waxing can injure the skin, which in turn leads to dark spots or patches

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When combined with a programmed cell death protein (PD-1) inhibitor, it displayed enhanced antitumor effects, all while exhibiting minimal toxicity to normal cells [99]

Glucose has to be phosphorylated to activate glycogen synthase, but not to inactivate glycogen phosphorylase in hepatocytes

Nat Rev Drug Discov (2020) 20:10124

RBCs (red blood cells) carry oxygen (O2) from the lungs to the organs and remove carbon dioxide (CO2) when we breathe out