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Reference: Malinda KM et al

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

SALT score dropped from 40% to 7.5% The median SALT score decreased from 40.0% (IQR: 23.8%50.0%) at baseline to 7.5% (IQR: 0%17.5%) after 5 sessions

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Further analysis showed that Stigmasterol could induce apoptosis and activate the mitochondrial apoptosis signaling pathway